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Worry wrinkles and forehead wrinkles – treatment alternatives In principle facial wrinkles can be treated with fillers such as collagen, hyaluronic acid or through muscle relaxing substances like Botulinumtoxin – A. The goal of wrinkle treatment is a long lasting smoothening and conservation of the skin. Muscle relaxing substances work by preventing the effect of muscle tension and thereby remove existing wrinkles. The effects of muscle relaxing substances are limited in duration and treatment and must be repeated after ca. six months' time. Worry wrinkles and wrinkling of the forehead can be preserved and smoothed by using muscle-relaxing substances. In cases of further advanced wrinkling, a combination of filler and muscle relaxants are used. 
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